Paternal RLIM/Rnf12 Is a Survival Factor for Milk-Producing Alveolar Cells
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منابع مشابه
Paternal RLIM/Rnf12 Is a Survival Factor for Milk-Producing Alveolar Cells
In female mouse embryos, somatic cells undergo a random form of X chromosome inactivation (XCI), whereas extraembryonic trophoblast cells in the placenta undergo imprinted XCI, silencing exclusively the paternal X chromosome. Initiation of imprinted XCI requires a functional maternal allele of the X-linked gene Rnf12, which encodes the ubiquitin ligase Rnf12/RLIM. We find that knockout (KO) of ...
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ژورنال
عنوان ژورنال: Cell
سال: 2012
ISSN: 0092-8674
DOI: 10.1016/j.cell.2012.02.056